Description

7-Ethynyl-1H-Indazole is a high-value, heterocyclic organic compound featuring a fused indazole core with an ethynyl substituent. This unique structure makes it a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides.
• Chemical Synthesis: Used in cross-coupling reactions (e.g., Sonogashira) to construct complex molecular architectures for material science.
• Biochemical Tool Compound: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and biological screening.
• Academic & Industrial R&D: Fundamental research reagent for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	7-Ethynyl-1H-Indazole
CAS No.	945761-99-9
Molecular Formula	C9H6N2
Molecular Weight	142.16 g/mol
Synonyms	7-Ethynyl-1H-indazole; 1H-Indazole, 7-ethynyl-; 7-Ethynylindazole; 7-Ethynyl-1H-indazole; 945761-99-9; 7-Ethynylindazole; 7-Ethynyl-1H-indazole (CAS 945761-99-9)
EINECS	Contact for details

Quality Control

Our 7-Ethynyl-1H-Indazole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.