Description

Glycine, n-[(1-Cyano-4,7-Dihydroxy-3-Isoquinolinyl)Carbonyl]- is a specialized, high-purity synthetic intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in advanced pharmaceutical research and development, particularly for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries working on innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those with isoquinoline-based scaffolds.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Bioconjugation Chemistry: The glycine moiety and reactive functional groups can be utilized for linking molecules in probe or drug conjugate development.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex organic compounds in custom synthesis projects.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Glycine, n-[(1-Cyano-4,7-Dihydroxy-3-Isoquinolinyl)Carbonyl]-
CAS No.	945740-15-8
Molecular Formula	C13H9N3O5
Molecular Weight	287.23 g/mol
Synonyms	N-[(1-Cyano-4,7-dihydroxyisoquinolin-3-yl)carbonyl]glycine; 2-[[(1-Cyano-4,7-dihydroxy-3-isoquinolinyl)carbonyl]amino]acetic acid; Glycine, N-[(1-cyano-4,7-dihydroxy-3-isoquinolinyl)carbonyl]-; 945740-15-8; 1-Cyano-4,7-dihydroxy-3-isoquinolinecarboxylic acid glycine amide; Isoquinoline-glycine conjugate
EINECS	Contact for details

Quality Control

Our Glycine, n-[(1-Cyano-4,7-Dihydroxy-3-Isoquinolinyl)Carbonyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.