Description

Glycine, n-[[1-Cyano-4-Hydroxy-7-(Phenylmethyl)-3-Isoquinolinyl]Carbonyl]- is a specialized, high-purity chemical building block designed for advanced research and synthesis. This compound is critical for the development of novel pharmaceutical intermediates and active ingredients, particularly in oncology and targeted therapy research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and optimizing new chemical entities (NCEs) with potential therapeutic activity.
• Protease Inhibitor Development: Applied in the research and development of inhibitors for specific proteases, given its structural features common to isoquinoline-based inhibitors.
• Biochemical Reagent: Employed in biochemical assays and as a tool compound for studying biological mechanisms and target validation.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to construct complex heterocyclic molecules for various high-value applications.

Basic Information

Product Name	Glycine, n-[[1-Cyano-4-Hydroxy-7-(Phenylmethyl)-3-Isoquinolinyl]Carbonyl]-
CAS No.	945739-84-4
Molecular Formula	C20H15N3O3
Molecular Weight	345.35 g/mol
Synonyms	N-[(1-Cyano-4-hydroxy-7-benzylisoquinolin-3-yl)carbonyl]glycine; Glycine, N-[(1-cyano-4-hydroxy-7-benzyl-3-isoquinolinyl)carbonyl]-; 1-Cyano-4-hydroxy-7-benzyl-3-isoquinolinecarboxylic acid glycine amide; 7-Benzyl-1-cyano-4-hydroxy-N-(carboxymethyl)isoquinoline-3-carboxamide; 3-Isoquinolinecarboxamide, 7-(phenylmethyl)-1-cyano-4-hydroxy-, N-(carboxymethyl)-
EINECS	Contact for details

Quality Control

Our Glycine, n-[[1-Cyano-4-Hydroxy-7-(Phenylmethyl)-3-Isoquinolinyl]Carbonyl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques like HPLC and NMR. We adhere to cGMP guidelines where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.