Description

Glycine, n-[(7-Chloro-1-Cyano-4-Hydroxy-3-Isoquinolinyl)Carbonyl]- is a specialized, high-purity synthetic intermediate featuring a unique isoquinoline core structure. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and complex heterocyclic molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with complex isoquinoline-based structures.
• Fine Chemical Synthesis: Serves as a precursor for creating specialized dyes, pigments, or functional materials requiring the chlorinated isoquinoline moiety.
• Bioconjugation & Probe Development: The reactive carbonyl group on the glycine moiety can be utilized for coupling reactions in bioconjugate chemistry or diagnostic probe synthesis.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and CROs (Contract Research Organizations) exploring new chemical entities.

Basic Information

Item	Detail
Product Name	Glycine, n-[(7-Chloro-1-Cyano-4-Hydroxy-3-Isoquinolinyl)Carbonyl]-
CAS No.	945739-70-8
Molecular Formula	C13H8ClN3O3
Molecular Weight	289.67 g/mol
Synonyms	N-[(7-Chloro-1-cyano-4-hydroxyisoquinolin-3-yl)carbonyl]glycine; 2-[[(7-Chloro-1-cyano-4-hydroxy-3-isoquinolinyl)carbonyl]amino]acetic acid; Glycine, N-[(7-chloro-1-cyano-4-hydroxy-3-isoquinolinyl)carbonyl]-; 945739-70-8; 7-Chloro-1-cyano-4-hydroxy-3-isoquinolinecarboxylic acid glycine amide
EINECS	Contact for details

Quality Control

Our production of Glycine, n-[(7-Chloro-1-Cyano-4-Hydroxy-3-Isoquinolinyl)Carbonyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handle and store under an inert atmosphere if recommended for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.