Description

Ethyl 6-Amino-2-Phenyl-1H-Indole-3-Carboxylate is a high-purity indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and the synthesis of novel heterocyclic compounds. CAS No. 945655-38-9.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new crop protection agents and pesticides.
• Organic Synthesis Building Block: Employed in the construction of complex indole-based heterocycles for material science and specialty chemical applications.
• Biochemical Research: Potential use in developing fluorescent probes or enzyme inhibitors due to its indole core structure.

Basic Information

Product Name	Ethyl 6-Amino-2-Phenyl-1H-Indole-3-Carboxylate
CAS No.	945655-38-9
Molecular Formula	C₁₇H₁₆N₂O₂
Molecular Weight	280.32 g/mol
Synonyms	6-Amino-2-phenyl-1H-indole-3-carboxylic acid ethyl ester; Ethyl 6-amino-2-phenylindole-3-carboxylate; 2-Phenyl-6-aminoindole-3-carboxylic acid ethyl ester; 945655-38-9; 6-Amino-2-phenylindole-3-carboxylate ethyl ester; Ethyl α-(6-amino-2-phenyl-1H-indol-3-yl)acetate (common misnomer); 1H-Indole-3-carboxylic acid, 6-amino-2-phenyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Amino-2-Phenyl-1H-Indole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.