Description

1-(2-Bromophenyl)-5-Methoxy-1H-Indole is a high-purity, specialized brominated indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its modifiable indole core.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Material Science Precursor: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, where its conjugated system is valuable.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and exploratory synthesis projects.
• Custom Synthesis & Scale-Up: A starting material for the custom manufacturing of complex, high-value target molecules for various industrial clients.

Basic Information

Product Name	1-(2-Bromophenyl)-5-Methoxy-1H-Indole
CAS No.	945472-59-3
Molecular Formula	C15H12BrNO
Molecular Weight	302.17 g/mol
Synonyms	5-Methoxy-1-(2-bromophenyl)-1H-indole; 1H-Indole, 1-(2-bromophenyl)-5-methoxy-; 1-(2-Bromophenyl)-5-methoxyindole; 5-Methoxy-1-(o-bromophenyl)indole; 1-(2-Bromophenyl)-5-methoxy-1H-indole; 945472-59-3; 2-Bromo-5-methoxy-1-phenyl-1H-indole (isomer); 1-(2-Bromophenyl)-5-methoxyindole
EINECS	Contact for details

Quality Control

Our 1-(2-Bromophenyl)-5-Methoxy-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.