Description

4-Methyl-1,4Lambda5-Azaphosphinan-4-One Hydrochloride is a high-purity, specialized organophosphorus compound offered under CAS NO 945459-80-3. This chemical is a valuable synthetic intermediate, prized for its unique heterocyclic structure containing both phosphorus and nitrogen, which enables its use in advanced chemical synthesis. It is primarily sought by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, insecticides, or plant growth regulators, leveraging its phosphorus-containing heterocycle.
• Ligand & Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated for incorporation into polymers or coatings to impart specific flame-retardant or chemical resistance properties.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or as a molecular probe due to its phosphoryl group.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of complex molecules.

Basic Information

Product Name	4-Methyl-1,4Lambda5-Azaphosphinan-4-One Hydrochloride
CAS No.	945459-80-3
Molecular Formula	C6H13ClNOP
Molecular Weight	181.60 g/mol
Synonyms	4-Methyl-1,4-azaphosphinan-4-one hydrochloride; 4-Methyl-1,4-azaphosphorinan-4-one hydrochloride; 1,4-Azaphosphinan-4-one, 4-methyl-, hydrochloride; 4-Methyl-1,4-azaphosphinane-4-one HCl; 4-Methyl-1,4-azaphosphorinane-4-one hydrochloride; 4-Methyl-4-oxo-1,4-azaphosphinane hydrochloride; 4-Methyl-1,4-azaphosphinane-4-one hydrochloride salt
EINECS	Contact for details

Quality Control

Our 4-Methyl-1,4Lambda5-Azaphosphinan-4-One Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.