Description

1H-Indole-2-Thiol, 1-Methyl-5-Nitro- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific biological pathways. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, as well as by manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those with indole-based scaffolds for neurological or oncological targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials and specialty polymers requiring specific functional groups.
• Biochemical Probe Synthesis: Utilized in creating labeled compounds or probes for studying biological mechanisms and enzyme interactions.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Product Name	1H-Indole-2-Thiol, 1-Methyl-5-Nitro-
CAS No.	945454-10-4
Molecular Formula	C9H8N2O2S
Molecular Weight	208.24 g/mol
Synonyms	1-Methyl-5-nitro-1H-indole-2-thiol; 5-Nitro-1-methyl-1H-indole-2-thiol; 1-Methyl-5-nitroindole-2-thiol; 2-Mercapto-1-methyl-5-nitroindole; 1-Methyl-5-nitroindole-2-thiol; 945454-10-4; SCHEMBL21833027; DTXSID60664669
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Thiol, 1-Methyl-5-Nitro- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.