Description

1H-Indole-2-Thiol, 5-Nitro-1-(2-Propen-1-Yl)- is a specialized heterocyclic organic compound featuring a nitro-substituted indole core with a thiol and an allyl functional group. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteomics research due to its reactive thiol group.
• Academic & Industrial R&D: A crucial reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	1H-Indole-2-Thiol, 5-Nitro-1-(2-Propen-1-Yl)-
CAS No.	945454-05-7
Molecular Formula	C11H10N2O2S
Molecular Weight	234.27 g/mol
Synonyms	5-Nitro-1-allyl-1H-indole-2-thiol; 1-Allyl-5-nitro-1H-indole-2-thiol; 1H-Indole-2-thiol, 5-nitro-1-(2-propen-1-yl)-; 5-Nitro-1-(prop-2-en-1-yl)-1H-indole-2-thiol; Allyl 5-nitroindole-2-thioether (precursor form); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-2-Thiol, 5-Nitro-1-(2-Propen-1-Yl)- is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from heat, sparks, and open flame. For long-term storage, consider sealing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.