Description

Acetamide, n-(5-Fluoro-2,3-Dihydro-2-Oxo-1H-Indol-6-Yl)- is a high-purity, specialized organic intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for the synthesis of complex heterocyclic molecules, where its unique indole-acetamide scaffold is critical.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Research & Development: Essential for medicinal chemistry programs in academic, biotech, and pharmaceutical R&D laboratories for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs containing the 5-fluoro-2-oxindole pharmacophore.
• Fine Chemical Production: Serves as a precursor for manufacturing other high-value, fluorinated specialty chemicals.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials.

Basic Information

Product Name	Acetamide, n-(5-Fluoro-2,3-Dihydro-2-Oxo-1H-Indol-6-Yl)-
CAS No.	945379-33-9
Molecular Formula	C10H9FN2O2
Molecular Weight	208.19 g/mol
Synonyms	6-Acetamido-5-fluoro-1,3-dihydro-2H-indol-2-one; 5-Fluoro-6-acetamidooxindole; N-(5-Fluoro-2-oxo-2,3-dihydro-1H-indol-6-yl)acetamide; 5-Fluoro-6-acetamido-1,3-dihydroindol-2-one; 945379-33-9; 6-Acetylamino-5-fluorooxindole; Acetamide, N-(5-fluoro-2,3-dihydro-2-oxo-1H-indol-6-yl)-
EINECS	Contact for details

Quality Control

Our Acetamide, n-(5-Fluoro-2,3-Dihydro-2-Oxo-1H-Indol-6-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.