Description

2-(3,4-Dihydroisoquinolin-2(1H)-Yl)Nicotinonitrile is a specialized organic compound belonging to the class of fused heterocyclic nitriles. This high-purity intermediate is of significant value in modern pharmaceutical research and development, particularly for its role as a key building block in medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel pesticides and herbicides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Organic Synthesis: A versatile nitrile-containing intermediate for constructing complex polycyclic heterocyclic frameworks.

Basic Information

Product Name	2-(3,4-Dihydroisoquinolin-2(1H)-Yl)Nicotinonitrile
CAS No.	945347-37-5
Molecular Formula	C15H13N3
Molecular Weight	235.29 g/mol
Synonyms	2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)nicotinonitrile; 2-(3,4-Dihydro-1H-isoquinolin-2-yl)nicotinonitrile; Nicotinonitrile, 2-(1,2,3,4-tetrahydroisoquinolin-2-yl)-; 2-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-3-cyanopyridine; 3-Cyano-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dihydroisoquinolin-2(1H)-Yl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.