Description

2-{[2-(5-Fluoro-1H-Indol-3-Yl)Ethyl]Amino}-5-Nitrobenzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure combining indole and benzonitrile moieties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and oncological therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting serotonin receptors and kinase inhibition.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of assay probes and diagnostic reagents.
• Organic Synthesis: Valuable intermediate for constructing complex heterocyclic frameworks in academic and industrial research settings.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2-{[2-(5-Fluoro-1H-Indol-3-Yl)Ethyl]Amino}-5-Nitrobenzonitrile
CAS No.	945299-27-4
Molecular Formula	C₁₇H₁₃FN₄O₂
Molecular Weight	324.31 g/mol
Synonyms	5-Nitro-2-({2-[5-fluoro-1H-indol-3-yl]ethyl}amino)benzonitrile; 2-[(2-(5-Fluoro-1H-indol-3-yl)ethyl)amino]-5-nitrobenzonitrile; 945299-27-4; 5-Fluoro-3-[2-[(5-cyano-2-nitrophenyl)amino]ethyl]indole; N-[2-(5-Fluoro-1H-indol-3-yl)ethyl]-5-nitro-2-cyanobenzeneamine
EINECS	Contact for details

Quality Control

Our 2-{[2-(5-Fluoro-1H-Indol-3-Yl)Ethyl]Amino}-5-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.