Description

1H-Indazole, 3-Ethyl-5-Fluoro- CAS NO 945265-05-4 is a high-purity fluorinated indazole derivative, a crucial building block in modern organic synthesis. Its value lies in its unique molecular scaffold, which serves as a privileged structure for developing novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the indazole core.
• Material Science: Serves as a precursor for advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Ligand Synthesis: Useful for creating complex ligands in catalysis and coordination chemistry due to its nitrogen-containing heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Item	Detail
Product Name	1H-Indazole, 3-Ethyl-5-Fluoro-
CAS No.	945265-05-4
Molecular Formula	C9H9FN2
Molecular Weight	164.18 g/mol
Synonyms	3-Ethyl-5-fluoro-1H-indazole; 5-Fluoro-3-ethyl-1H-indazole; 3-Ethyl-5-fluoroindazole; 1H-Indazole, 3-ethyl-5-fluoro-; 945265-05-4; 3-Ethyl-5-fluoroindazole; 5-Fluoro-3-ethylindazole
EINECS	Contact for details

Quality Control

Our 1H-Indazole, 3-Ethyl-5-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.