Description

4-Chloro-2,5-Difluorobenzyl Bromide is a versatile and high-value halogenated benzyl bromide intermediate. This compound is critical for introducing the 4-chloro-2,5-difluorobenzyl moiety into more complex molecular architectures, enabling precise structural modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use in synthesis, particularly in the creation of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in medicinal chemistry for creating libraries of compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the difluorobenzyl group is a critical structural component.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for display technologies.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions to construct complex organic molecules.
• Chemical Research: Utilized in academic and industrial R&D settings for method development and exploring new chemical entities.
• Material Science: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	4-Chloro-2,5-Difluorobenzyl Bromide
CAS No.	945262-21-5
Molecular Formula	C7H4BrClF2
Molecular Weight	241.46 g/mol
Synonyms	1-(Bromomethyl)-4-chloro-2,5-difluorobenzene; (4-Chloro-2,5-difluorophenyl)methyl bromide; 4-Chloro-2,5-difluoro-α-bromotoluene; 4-Chloro-2,5-difluorobenzylbromide; 2,5-Difluoro-4-chlorobenzyl bromide; Benzene, 1-(bromomethyl)-4-chloro-2,5-difluoro-; α-Bromo-4-chloro-2,5-difluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,5-Difluorobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.