Description

6-tert-Butyl 2-Ethyl 4,5,7,8-Tetrahydrothieno[2,3-D]Azepine-2,6-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for research and development chemists, process scale-up engineers, and manufacturers in the global pharmaceutical and fine chemical industries who require reliable, high-quality raw materials for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel therapeutic agents, especially for neurological and psychiatric applications.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Process Chemistry: Employed in route scouting, optimization, and the scale-up manufacturing of target APIs under cGMP conditions.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic frameworks in custom synthesis projects.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Item	Details
Product Name	6-tert-Butyl 2-Ethyl 4,5,7,8-Tetrahydrothieno[2,3-D]Azepine-2,6-Dicarboxylate
CAS No.	945007-92-1
Molecular Formula	C17H25NO4S
Molecular Weight	339.45 g/mol
Synonyms	6-tert-Butyl 2-ethyl 4,5,7,8-tetrahydrothieno[2,3-d]azepine-2,6-dicarboxylate; Thieno[2,3-d]azepine-2,6-dicarboxylic acid, 4,5,7,8-tetrahydro-, 2-ethyl 6-(1,1-dimethylethyl) ester; 2-Ethyl 6-tert-butyl 4,5,7,8-tetrahydrothieno[2,3-d]azepine-2,6-dicarboxylate; tert-Butyl 2-ethyl 4,5,7,8-tetrahydrothieno[2,3-d]azepine-2,6-dicarboxylate; CAS 945007-92-1
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl 2-Ethyl 4,5,7,8-Tetrahydrothieno[2,3-D]Azepine-2,6-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.