Description

1-tert-Butyl 5-Methyl 3-Iodo-1H-Indazole-1,5-Dicarboxylate is a high-purity, synthetically valuable indazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a protected, functionalized scaffold that enables precise and efficient construction of complex molecules, particularly in pharmaceutical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing new crop protection agents and herbicides with enhanced efficacy.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and activity-based probes (ABPs) for studying enzyme function and protein interactions.
• Material Science: Potential monomer or functional additive in the development of advanced polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	1-tert-Butyl 5-Methyl 3-Iodo-1H-Indazole-1,5-Dicarboxylate
CAS No.	944904-57-8
Molecular Formula	C15H17IN2O4
Molecular Weight	416.21 g/mol
Synonyms	1-(tert-Butyl) 5-methyl 3-iodo-1H-indazole-1,5-dicarboxylate; 3-Iodo-1H-indazole-1,5-dicarboxylic acid 1-tert-butyl 5-methyl ester; tert-Butyl 5-methyl 3-iodo-1H-indazole-1,5-dicarboxylate; 1H-Indazole-1,5-dicarboxylic acid, 3-iodo-, 1-(1,1-dimethylethyl) 5-methyl ester; 944904-57-8; 3-Iodo-indazole-1,5-dicarboxylic acid tert-butyl methyl diester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 5-Methyl 3-Iodo-1H-Indazole-1,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.