Description

1H-Indazole-4-Carboxaldehyde, 3-Iodo- is a high-value, halogenated indazole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in the development of novel pharmaceutical agents and functional materials. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for use in medicinal chemistry, cross-coupling reactions, and as a versatile aldehyde building block.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Agrochemical Synthesis: Employed in the development of new active ingredients for crop protection products.
• Material Science: Serves as a building block for creating advanced organic materials, such as ligands for catalysts or organic semiconductors.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Chemical Biology Probes: Used to develop molecular probes for studying biological processes and target identification.

Basic Information

Product Name	1H-Indazole-4-Carboxaldehyde, 3-Iodo-
CAS No.	944904-44-3
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	3-Iodo-1H-indazole-4-carboxaldehyde; 3-Iodo-1H-indazole-4-carbaldehyde; 4-Formyl-3-iodo-1H-indazole; 3-Iodoindazole-4-carboxaldehyde; 944904-44-3; 3-Iodo-1H-indazole-4-carboxaldehyde; 3-Iodo-1H-indazole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1H-Indazole-4-Carboxaldehyde, 3-Iodo- is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder/crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.