Description

3-Iodo-2H-Indazole-7-Carbonitrile is a high-value, halogenated indazole derivative serving as a critical synthetic intermediate. Its molecular architecture, featuring both an iodine substituent and a nitrile group, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated indazole core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a probe or labeling reagent due to the reactivity of the iodine atom in cross-coupling reactions.
• Organic Synthesis: A versatile substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex functionalities.

Basic Information

Product Name	3-Iodo-2H-Indazole-7-Carbonitrile
CAS No.	944904-35-2
Molecular Formula	C8H4IN3
Molecular Weight	285.04 g/mol
Synonyms	7-Cyano-3-iodo-2H-indazole; 3-Iodo-1H-indazole-7-carbonitrile; 3-Iodo-2H-indazole-7-carbonitrile; 944904-35-2; 3-Iodoindazole-7-carbonitrile; 7-Cyano-3-iodoindazole; 3-Iodo-7-cyanoindazole; 2H-Indazole-7-carbonitrile, 3-iodo-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 3-Iodo-2H-Indazole-7-Carbonitrile adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by advanced analytical techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.