Description

tert-Butyl 3-(Chloromethyl)-1H-indazole-1-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its versatile indazole scaffold. This compound is of significant commercial importance for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting oncology, inflammation, and central nervous system (CNS) disorders.
• API Synthesis: Serves as a crucial building block for constructing complex molecular architectures in Active Pharmaceutical Ingredient (API) development pipelines.
• Agrochemical Research: Used in the research and development of new generation pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Item	Details
Product Name	tert-Butyl 3-(Chloromethyl)-1H-indazole-1-carboxylate
CAS No.	944899-34-7
Molecular Formula	C13H15ClN2O2
Molecular Weight	266.72 g/mol
Synonyms	1-Boc-3-(chloromethyl)-1H-indazole; 1-(tert-Butoxycarbonyl)-3-(chloromethyl)-1H-indazole; tert-Butyl 3-(chloromethyl)-1H-indazole-1-carboxylate; 3-(Chloromethyl)-1H-indazole-1-carboxylic acid tert-butyl ester; Boc-3-chloromethylindazole; 944899-34-7; 1H-Indazole-1-carboxylic acid, 3-(chloromethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-(Chloromethyl)-1H-indazole-1-carboxylate adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.