Description

3-Iodo-1H-Indazole-7-Carbaldehyde is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic positioning of reactive iodine and aldehyde functional groups on the indazole scaffold, enabling precise derivatization for complex molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, serving as a critical intermediate in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small molecule drugs, particularly kinase inhibitors and other enzyme modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and photoactive compounds.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bioconjugates for studying biological pathways.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Library Synthesis: Utilized in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.

Basic Information

Product Name	3-Iodo-1H-Indazole-7-Carbaldehyde
CAS No.	944899-03-0
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	7-Formyl-3-iodo-1H-indazole; 3-Iodo-1H-indazole-7-carboxaldehyde; 1H-Indazole-7-carboxaldehyde, 3-iodo-; 3-Iodo-7-indazolecarbaldehyde; 944899-03-0; 3-Iodoindazole-7-carbaldehyde; 7-Aldehyde-3-iodoindazole
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-1H-Indazole-7-Carbaldehyde is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.