Description

3-(1-Pyrrolidinylsulfonyl)-2-Thiophenecarboxylic Acid(Saltdata: 0.14Nacl) is a high-purity, specialized organic intermediate with a unique pyrrolidine-sulfonyl-thiophene carboxylic acid structure. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold in probe design.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	3-(1-Pyrrolidinylsulfonyl)-2-Thiophenecarboxylic Acid(Saltdata: 0.14Nacl)
CAS No.	944895-22-1
Molecular Formula	C9H11NO4S2 • xNaCl
Molecular Weight	261.32 g/mol (Free acid)
Synonyms	3-(Pyrrolidine-1-sulfonyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-(1-pyrrolidinylsulfonyl)-; 3-(1-Pyrrolidinosulfonyl)-2-thiophenecarboxylic acid; Pyrrolidine-1-sulfonyl-thiophene-2-carboxylic acid; 944895-22-1; 3-Pyrrolidin-1-ylsulfonyl-thiophene-2-carboxylic acid; Thiophene-2-carboxylic acid derivative (sulfonamide)
EINECS	Contact for details

Quality Control

Every batch of 3-(1-Pyrrolidinylsulfonyl)-2-Thiophenecarboxylic Acid(Saltdata: 0.14Nacl) is manufactured under strict quality management protocols. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods like HPLC, NMR, and MS. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.