Description

[3-(Morpholin-4-Ylsulfonyl)Thien-2-Yl]Methylamine is a high-purity, specialized organic building block featuring a unique thiophene core functionalized with a morpholinosulfonyl group and a primary amine. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Material Science: Serves as a precursor for functionalized monomers or ligands in the creation of advanced polymers and coordination complexes.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for target validation and biochemical pathway studies.
• Custom Synthesis: A versatile starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in bespoke chemical synthesis projects.

Basic Information

Product Name	[3-(Morpholin-4-Ylsulfonyl)Thien-2-Yl]Methylamine
CAS No.	944894-80-8
Molecular Formula	C9H14N2O3S2
Molecular Weight	262.35 g/mol
Synonyms	1-(3-Morpholin-4-ylsulfonylthiophen-2-yl)methanamine; 2-(Aminomethyl)-3-(morpholinosulfonyl)thiophene; 3-(Morpholine-4-sulfonyl)-2-thiophenemethylamine; (3-Morpholin-4-ylsulfonyl-thiophen-2-yl)-methylamine; 2-Thiophenemethylamine, 3-(4-morpholinylsulfonyl)-; 944894-80-8; 3-Morpholinosulfonyl-2-thiophenemethylamine
EINECS	Contact for details

Quality Control

Our [3-(Morpholin-4-Ylsulfonyl)Thien-2-Yl]Methylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.