Description

1-(4-Fluorobenzyl)-1H-Indole-5-Carbaldehyde is a high-purity fluorinated indole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which combines an indole core with a fluorinated benzyl group, making it an essential building block for creating complex molecules with targeted properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by specialty chemical manufacturers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-inflammatory compounds.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, where the fluorine atom and indole structure can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for functional organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals, due to its conjugated system.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and fluorescent tags for studying biological processes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	1-(4-Fluorobenzyl)-1H-Indole-5-Carbaldehyde
CAS No.	944893-59-8
Molecular Formula	C16H12FNO
Molecular Weight	253.27 g/mol
Synonyms	5-Formyl-1-[(4-fluorophenyl)methyl]-1H-indole; 1-[(4-Fluorophenyl)methyl]-1H-indole-5-carboxaldehyde; 1H-Indole-5-carboxaldehyde, 1-[(4-fluorophenyl)methyl]-; 1-(4-Fluorobenzyl)indole-5-carbaldehyde; 5-Carbaldehyde-1-(4-fluorobenzyl)indole; 1-(4-Fluorobenzyl)-5-formylindole; 1-(p-Fluorobenzyl)-1H-indole-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-1H-Indole-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.