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4-Bromo-2-Fluoro-1-(2-Methoxyethoxy)Benzene CAS NO 944279-01-0


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CAS No.:944279-01-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromo-2-Fluoro-1-(2-Methoxyethoxy)Benzene is a high-purity, multi-functional aromatic ether building block designed for advanced synthetic chemistry. This compound is valued for its unique halogenated and alkoxy-substituted benzene structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery, material science, and the synthesis of specialty chemicals.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and ether functionalities.
  • Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
  • Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination due to the reactive bromine atom.
  • Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.
  • Ligand and Catalyst Design: The methoxyethoxy side chain can be utilized to modify the solubility and electronic properties of catalytic ligands.

Basic Information

Product Name 4-Bromo-2-Fluoro-1-(2-Methoxyethoxy)Benzene
CAS No. 944279-01-0
Molecular Formula C9H10BrFO2
Molecular Weight 249.08 g/mol
Synonyms 1-Bromo-4-fluoro-2-(2-methoxyethoxy)benzene; 2-(2-Methoxyethoxy)-4-bromo-1-fluorobenzene; 4-Bromo-2-fluoro-1-(2-methoxyethoxy)benzene; 1-Fluoro-2-(2-methoxyethoxy)-4-bromobenzene; Benzene, 1-bromo-4-fluoro-2-(2-methoxyethoxy)-; 944279-01-0; AKOS005258155
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Quality Control

Our 4-Bromo-2-Fluoro-1-(2-Methoxyethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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