Description

4-Isoquinolinecarboxamide, 1,2,3,4-Tetrahydro-3-(1H-Indol-3-Yl)-2-(2-Methoxyethyl)-n-(2-Methoxy-5-Methylphenyl)-1-Oxo-, (3R,4R)-Rel- CAS NO 943934-76-7 is a high-purity, stereochemically defined organic compound belonging to a complex class of fused heterocyclic molecules. This compound is of significant value as a key synthetic intermediate or a potential pharmacophore in advanced research and development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

This specialized chemical intermediate serves critical roles in advanced scientific and industrial applications:

• Pharmaceutical Research & Development: As a core building block for the synthesis of novel drug candidates targeting neurological or oncological pathways.
• Medicinal Chemistry: For structure-activity relationship (SAR) studies and lead optimization due to its complex, multi-functional molecular architecture.
• Biochemical Research: Potential use as a tool compound or a ligand in enzyme inhibition assays and receptor binding studies.
• Process Chemistry Development: Serving as a critical intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and institutes for pioneering studies in organic synthesis methodologies and heterocyclic chemistry.
• Contract Research Organizations (CROs): Supplied to CROs supporting drug discovery projects for client pharmaceutical companies.

Basic Information

Product Name	4-Isoquinolinecarboxamide, 1,2,3,4-Tetrahydro-3-(1H-Indol-3-Yl)-2-(2-Methoxyethyl)-n-(2-Methoxy-5-Methylphenyl)-1-Oxo-, (3R,4R)-Rel-
CAS No.	943934-76-7
Molecular Formula	C29H31N3O4
Molecular Weight	485.58 g/mol
Synonyms	(3R,4R)-rel-1,2,3,4-Tetrahydro-3-(1H-indol-3-yl)-2-(2-methoxyethyl)-N-(2-methoxy-5-methylphenyl)-1-oxo-4-isoquinolinecarboxamide; (3R,4R)-1,2,3,4-Tetrahydro-3-(1H-indol-3-yl)-2-(2-methoxyethyl)-N-(2-methoxy-5-methylphenyl)-1-oxo-4-isoquinolinecarboxamide; rel-(3R,4R)-1,2,3,4-Tetrahydro-3-(1H-indol-3-yl)-2-(2-methoxyethyl)-N-(2-methoxy-5-methylphenyl)-1-oxo-4-isoquinolinecarboxamide; 4-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-3-(1H-indol-3-yl)-2-(2-methoxyethyl)-N-(2-methoxy-5-methylphenyl)-1-oxo-, (3R,4R)-rel-; CAS 943934-76-7
EINECS	Contact for details

Quality Control

Our high-purity chemical intermediates are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and NMR/LC-MS for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.