Description

1H-Indazole-5-Methanamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial and research interest. Its value lies in its role as a versatile synthon for constructing complex molecules, particularly in medicinal chemistry and drug discovery. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting various enzyme families and receptors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Institutional R&D: A critical reagent for universities and research institutes exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	1H-Indazole-5-Methanamine Hydrochloride
CAS No.	943845-78-1
Molecular Formula	C8H10ClN3
Molecular Weight	183.64 g/mol
Synonyms	5-(Aminomethyl)-1H-indazole hydrochloride; 1H-Indazole-5-methanamine, hydrochloride; 5-(Aminomethyl)indazole hydrochloride; (1H-Indazol-5-yl)methanamine hydrochloride; 5-Aminomethylindazole HCl; Indazole-5-methylamine hydrochloride; 943845-78-1; SCHEMBL2180627
EINECS	Contact for details

Quality Control

Our 1H-Indazole-5-Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.