Description

1H-Indole, 3-[2-(3-Methyl-4-Nitro-5-Isoxazolyl)Ethenyl]- is a specialized heterocyclic organic compound featuring a unique indole-isoxazole hybrid structure, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the development of novel pharmacophores and functional materials with tailored properties. This high-purity building block is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for targeting neurological and anti-inflammatory pathways.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its conjugated π-system.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology research.
• Fine Chemical Synthesis: Used in multi-step syntheses of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	1H-Indole, 3-[2-(3-Methyl-4-Nitro-5-Isoxazolyl)Ethenyl]-
CAS No.	943835-00-5
Molecular Formula	C₁₄H₁₁N₃O₃
Molecular Weight	269.26 g/mol
Synonyms	3-[2-(3-Methyl-4-nitro-5-isoxazolyl)ethenyl]-1H-indole; (E)-3-(2-(3-Methyl-4-nitroisoxazol-5-yl)vinyl)-1H-indole; 3-[(E)-2-(3-Methyl-4-nitro-1,2-oxazol-5-yl)ethenyl]-1H-indole; 5-[(E)-2-(1H-Indol-3-yl)ethenyl]-3-methyl-4-nitroisoxazole; Indole-isoxazole hybrid; 943835-00-5; Light-sensitive indole derivative
EINECS	Contact for details

Quality Control

Our production of 1H-Indole, 3-[2-(3-Methyl-4-Nitro-5-Isoxazolyl)Ethenyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical R&D and scale-up processes. Each lot is fully characterized and undergoes rigorous analytical testing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or using amber glass containers where practical.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.