Description

Pyrrolidine, 2-[Diphenyl[(Trimethylsilyl)Oxy]Methyl]-, (2R)- is a high-value, chiral organosilicon compound featuring a pyrrolidine scaffold. This molecule is of significant interest in advanced organic synthesis, particularly as a versatile chiral building block or ligand for asymmetric catalysis. It is primarily utilized by research and development chemists in the pharmaceutical and fine chemical industries. The compound is supplied to exacting standards to ensure consistent performance in critical synthetic pathways.

Application

• Chiral Auxiliary or Ligand: Employed in asymmetric synthesis to induce chirality in target molecules, crucial for creating single-enantiomer active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel therapeutic agents, especially those targeting the central nervous system.
• Organocatalyst Component: Used in the development of metal-free catalytic systems for enantioselective transformations.
• Advanced Material Research: Investigated as a monomer or functional additive in the synthesis of specialized polymers with unique optical or electronic properties.
• Methodology Development: A valuable reagent for academic and industrial research focused on new synthetic methodologies involving silicon-protected intermediates.

Basic Information

Product Name	Pyrrolidine, 2-[Diphenyl[(Trimethylsilyl)Oxy]Methyl]-, (2R)-
CAS No.	943757-71-9
Molecular Formula	C20H27NOSi
Molecular Weight	325.52 g/mol
Synonyms	(2R)-2-[Diphenyl(trimethylsilyloxy)methyl]pyrrolidine; (R)-2-(Diphenyl((trimethylsilyl)oxy)methyl)pyrrolidine; (R)-2-[Hydroxy(diphenyl)methyl]-1-(trimethylsilyl)pyrrolidine; TMS-protected diphenylpyrrolidinol; Chiral pyrrolidine silyl ether; (R)-α-(Trimethylsiloxy)diphenylmethylpyrrolidine; (R)-TMS-DPMP
EINECS	Contact for details

Quality Control

Every batch of Pyrrolidine, 2-[Diphenyl[(Trimethylsilyl)Oxy]Methyl]-, (2R)- is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.