Description

1H-Indole-1-Carboxylic Acid, 2-Borono-4-(3-Hydroxy-3-Methylbutyl)-6-[[Methyl(1,2,2-Trimethylpropyl)Amino]Methyl]-, 1-(1,1-Dimethylethyl) Ester is a sophisticated, high-value boronic acid ester derivative of indole, designed for advanced synthetic applications. This compound matters as a critical building block and intermediate in modern pharmaceutical and agrochemical research, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting protease enzymes or requiring boron-containing pharmacophores.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile organoboron reagent for forming carbon-carbon bonds, essential for constructing complex heterocyclic systems.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Agrochemical Development: Employed as an intermediate in the research and synthesis of new generation herbicides or fungicides with specific modes of action.
• Chemical Biology Probes: Utilized in the development of activity-based probes or inhibitors for studying enzymatic processes and biological pathways.
• Advanced Material Synthesis: Potential use as a monomer or functionalizing agent in the creation of specialty polymers or organic electronic materials.

Basic Information

Item	Detail
Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-4-(3-Hydroxy-3-Methylbutyl)-6-[[Methyl(1,2,2-Trimethylpropyl)Amino]Methyl]-, 1-(1,1-Dimethylethyl) Ester
CAS No.	943637-14-7
Molecular Formula	C24H39BN2O4
Molecular Weight	430.39 g/mol
Synonyms	tert-Butyl 2-borono-4-(3-hydroxy-3-methylbutyl)-6-[[methyl(1,2,2-trimethylpropyl)amino]methyl]-1H-indole-1-carboxylate; 2-Boron-1-(tert-butoxycarbonyl)-4-(3-hydroxy-3-methylbutyl)-6-[(methylneopentylamino)methyl]indole; Boronic acid, B-[1-[[(1,1-dimethylethoxy)carbonyl]-4-(3-hydroxy-3-methylbutyl)-6-[[methyl(1,2,2-trimethylpropyl)amino]methyl]-1H-indol-2-yl]-; 943637-14-7; Advanced Pharmaceutical Intermediate 943637-14-7; Boronic Ester Indole Derivative
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 2-Borono-4-(3-Hydroxy-3-Methylbutyl)-6-[[Methyl(1,2,2-Trimethylpropyl)Amino]Methyl]-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccated environment to prevent degradation. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.