Description

6-Methyl-5-Nitroisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate and a versatile building block in organic synthesis. This compound matters for its critical role in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research targeting complex heterocyclic structures. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise chemical to enable the synthesis of potential drug candidates and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for designing and synthesizing novel compounds for biological screening.
• Organic Synthesis: Serves as a versatile reagent for constructing complex isoquinoline-based heterocycles in academic and industrial research.
• Agrochemical Development: Potential intermediate in the research and development of new crop protection agents and pesticides.
• Material Science Research: Investigated for the synthesis of organic electronic materials, dyes, or photoactive compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	6-Methyl-5-Nitroisoquinolin-1(2H)-One
CAS No.	943606-85-7
Molecular Formula	C₁₀H₈N₂O₃
Molecular Weight	204.19 g/mol
Synonyms	6-Methyl-5-nitro-1(2H)-isoquinolinone; 5-Nitro-6-methyl-1,2-dihydroisoquinolin-1-one; 1(2H)-Isoquinolinone, 6-methyl-5-nitro-; 6-Methyl-5-nitroisoquinolin-1-ol (tautomer); 6-Methyl-5-nitro-2H-isoquinolin-1-one; 5-Nitro-6-methylisoquinolin-1(2H)-one; 6-Methyl-5-nitro-1,2-dihydroisoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 6-Methyl-5-Nitroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.