Description

3-Bromophenyl Boronic Acid, n-Methylcarboxy-n-Methylglycinate is a specialized organoboron compound that serves as a high-value synthetic intermediate. Its molecular architecture, combining a boronic acid moiety with a functionalized glycinate ester, makes it a critical reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its precise structure enables targeted molecular modifications essential for drug discovery and advanced material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl halides and boronic acids, a cornerstone reaction in modern medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating novel bidentate ligands used in asymmetric catalysis and transition metal complexes.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors and emissive layer materials for electronic displays and lighting.
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological pathways and protein interactions.

Basic Information

Item	Detail
Product Name	3-Bromophenyl Boronic Acid, n-Methylcarboxy-n-Methylglycinate
CAS No.	943552-25-8
Molecular Formula	C11H13BBrNO5
Molecular Weight	330.94 g/mol
Synonyms	(3-Bromophenyl)boronic acid N-methylcarboxy-N-methylglycinate; 3-Bromobenzeneboronic acid glycinate ester; Methyl 2-((3-bromophenyl)boronyloxy)-2-methylacetate; Boronic acid, B-(3-bromophenyl)-, 2-methoxy-2-oxoethyl methyl ester; CAS 943552-25-8
EINECS	Contact for details

Quality Control

Every batch of 3-Bromophenyl Boronic Acid, n-Methylcarboxy-n-Methylglycinate is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure the material meets the exacting standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.