Description

Spiro[Cyclohexane-1,7'-[7H]Pyrrolo[1,2-A]Imidazol]-4-Ol, 5',6'-Dihydro-2'-(6-Methyl-2-Pyridinyl)-3'-(6-Quinoxalinyl)-, trans- is a complex, high-purity spirocyclic organic compound with significant potential in advanced pharmaceutical research and development. This molecule is valued for its unique three-dimensional structure, which is often critical for achieving high selectivity and potency in drug discovery, particularly in targeting challenging biological pathways. It serves as a key intermediate or pharmacophore for medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors, enabling the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel small-molecule drug candidates, particularly for central nervous system (CNS) or oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize drug-like properties such as potency, selectivity, and metabolic stability.
• Protease or Kinase Inhibitor Development: Its spirocyclic and heterocyclic architecture makes it suitable for designing inhibitors of specific enzyme families.
• Chemical Biology Probes: Utilized in the development of tool compounds to study and validate new biological targets and pathways.
• Preclinical Candidate Synthesis: Serves as an advanced intermediate in the multi-step synthesis of compounds selected for preclinical development.

Basic Information

Product Name	Spiro[Cyclohexane-1,7'-[7H]Pyrrolo[1,2-A]Imidazol]-4-Ol, 5',6'-Dihydro-2'-(6-Methyl-2-Pyridinyl)-3'-(6-Quinoxalinyl)-, trans-
CAS No.	943515-07-9
Molecular Formula	C24H23N5O
Molecular Weight	397.48 g/mol
Synonyms	trans-5',6'-Dihydro-2'-(6-methyl-2-pyridinyl)-3'-(6-quinoxalinyl)spiro[cyclohexane-1,7'-[7H]pyrrolo[1,2-a]imidazol]-4-ol; (trans)-2'-(6-Methylpyridin-2-yl)-3'-(quinoxalin-6-yl)-5',6'-dihydrospiro[cyclohexane-1,7'-pyrrolo[1,2-a]imidazol]-4'-ol; Spirocyclic pyrroloimidazole derivative; CAS 943515-07-9.
EINECS	Contact for details

Quality Control

Our Spiro[Cyclohexane-1,7'-[7H]Pyrrolo[1,2-A]Imidazol]-4-Ol, 5',6'-Dihydro-2'-(6-Methyl-2-Pyridinyl)-3'-(6-Quinoxalinyl)-, trans- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.