Description

1H-Pyrrolo[2,3-B]Pyridine, 4-(5-Nitro-2-Thienyl)-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this material for its precise molecular architecture, which enables the exploration of new drug candidates with potential for enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science: Acts as a monomer or functional additive in the research of advanced organic electronic materials and specialty polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and CROs (Contract Research Organizations) focused on heterocyclic chemistry.
• Process Chemistry Development: Employed by process chemists to scale up and optimize synthetic routes for target molecules in pilot plants.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-(5-Nitro-2-Thienyl)-1-(Phenylsulfonyl)-
CAS No.	943321-85-5
Molecular Formula	C17H11N3O4S2
Molecular Weight	385.42 g/mol
Synonyms	4-(5-Nitro-2-thienyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-4-(5-nitro-2-thienyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-(5-nitro-2-thienyl)-1-(phenylsulfonyl)-; 943321-85-5; 4-(5-Nitrothiophen-2-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-(5-Nitro-2-Thienyl)-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and compliance documentation for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.