Description

Ethanone, 1-(4-Iodo-5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-1-Yl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of targeted small-molecule therapeutics, offering precise chemical functionality for drug discovery and development. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects involving kinase inhibitors and other novel oncology or antiviral agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Serves as a core structural component in the design and synthesis of novel kinase-targeted therapeutic candidates.
• Bioconjugation & Probe Synthesis: Utilized in the creation of chemical probes for biochemical assays and target identification studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and scale-up.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Ethanone, 1-(4-Iodo-5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-1-Yl)-
CAS No.	942920-18-5
Molecular Formula	C10H9IN2O
Molecular Weight	300.10 g/mol
Synonyms	1-(4-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)ethanone; 4-Iodo-5-methyl-1-(1-oxoethyl)-1H-pyrrolo[2,3-b]pyridine; 1-Acetyl-4-iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine; 942920-18-5; 4-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4-Iodo-5-Methyl-1H-Pyrrolo[2,3-B]Pyridin-1-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with full chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.