Description

4-Bromo-3-Fluorobenzenethiol is a versatile aromatic thiol building block characterized by its bromo and fluoro substituents, which confer unique reactivity and electronic properties. This compound is essential for introducing the thiol functional group into complex molecular architectures, enabling the synthesis of advanced materials and pharmaceuticals. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications such as ligand synthesis, polymer modification, and as a key intermediate in cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders and cancers.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the thiol group for bioactivity.
• Ligand and Catalyst Preparation: Acts as a precursor for metal-chelating ligands in homogeneous catalysis and material science applications.
• Polymer and Material Science: Employed in the modification of polymers and surfaces through thiol-ene "click" chemistry or as a chain transfer agent.
• Organic Synthesis Reagent: Functions as a nucleophile in substitution reactions or as a protecting group for other functionalities in multi-step synthetic routes.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry research in both academic and industrial R&D laboratories.

Basic Information

Product Name	4-Bromo-3-Fluorobenzenethiol
CAS No.	942473-86-1
Molecular Formula	C6H4BrFS
Molecular Weight	207.06 g/mol
Synonyms	3-Fluoro-4-bromobenzenethiol; 4-Bromo-3-fluorothiophenol; 1-Bromo-2-fluoro-6-mercaptobenzene; (4-Bromo-3-fluorophenyl)thiol; Benzenethiol, 4-bromo-3-fluoro-; 942473-86-1; 4-Bromo-3-fluoro-benzenethiol
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Fluorobenzenethiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.