Description

3-Bromo-4-Fluorobenzenethiol is a versatile organosulfur building block characterized by its reactive thiol (-SH) group and halogen substituents. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate for introducing sulfur-containing moieties. It is primarily utilized by research chemists and process development scientists in fine chemical synthesis, material science, and ligand development.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing aryl thioether or disulfide linkages.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiol group.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Ligand & Catalyst Preparation: Serves as a precursor for creating chelating ligands in transition metal catalysis and coordination chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic compound formation.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing sulfur-containing aroma compounds, subject to purity and regulatory compliance.

Basic Information

Product Name	3-Bromo-4-Fluorobenzenethiol
CAS No.	942473-85-0
Molecular Formula	C6H4BrFS
Molecular Weight	207.06 g/mol
Synonyms	3-Bromo-4-fluorobenzenethiol; 4-Fluoro-3-bromobenzenethiol; 3-Bromo-4-fluorophenyl mercaptan; (3-Bromo-4-fluorophenyl)thiol; Benzenethiol, 3-bromo-4-fluoro-; 942473-85-0; 3-Br-4-F-C6H3SH
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorobenzenethiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.