Description

5-Fluoro-3-[(Pyrrolidin-1-Yl)Methyl]-1H-Indole is a high-value, fluorinated indole derivative that serves as a critical building block in modern synthetic organic chemistry. Its molecular architecture, featuring both a fluorine substituent and a pyrrolidine-containing side chain, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• Agrochemical Development: Serves as a precursor in the synthesis of advanced crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel compound synthesis.

Basic Information

Product Name	5-Fluoro-3-[(Pyrrolidin-1-Yl)Methyl]-1H-Indole
CAS No.	942404-20-8
Molecular Formula	C₁₃H₁₅FN₂
Molecular Weight	218.27 g/mol
Synonyms	5-Fluoro-3-(pyrrolidin-1-ylmethyl)-1H-indole; 1H-Indole, 5-fluoro-3-[(pyrrolidin-1-yl)methyl]-; 942404-20-8; 5-Fluoro-3-(1-pyrrolidinylmethyl)indole; 3-[(Pyrrolidin-1-yl)methyl]-5-fluoro-1H-indole; 5-Fluoro-3-pyrrolidin-1-ylmethyl-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-[(Pyrrolidin-1-Yl)Methyl]-1H-Indole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.