Description

5-Chloro-2-(Trifluoromethyl)Benzylamine is a high-purity, versatile benzylamine derivative featuring both chloro and trifluoromethyl substituents, making it a valuable synthon for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique structure enables the creation of novel active ingredients. It is primarily sought by fine chemical manufacturers, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Custom Synthesis and Scal-up: A starting material for contract manufacturing organizations (CMOs) performing custom synthesis for client-specific molecular targets.

Basic Information

Item	Details
Product Name	5-Chloro-2-(Trifluoromethyl)Benzylamine
CAS No.	942319-05-3
Molecular Formula	C8H7ClF3N
Molecular Weight	209.60 g/mol
Synonyms	(5-Chloro-2-(trifluoromethyl)phenyl)methanamine; 1-(Aminomethyl)-5-chloro-2-(trifluoromethyl)benzene; 5-Chloro-α-(trifluoromethyl)benzylamine; 2-(Trifluoromethyl)-5-chlorobenzylamine; α-Amino-5-chloro-α,α,α-trifluoro-o-xylene; 5-Chloro-2-trifluoromethylbenzylamine; Benzenemethanamine, 5-chloro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethyl)Benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.