Description

3-Thiophenemethanamine, 5-Chloro- is a high-purity, halogenated heterocyclic amine building block of significant interest in advanced organic synthesis. Its core value proposition lies in its unique molecular architecture, which combines a reactive primary amine group with a substituted thiophene ring, enabling the construction of complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of conductive polymers, organic semiconductors, and specialty coatings.
• Ligand and Catalyst Development: Employed to create novel chelating ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Thiophenemethanamine, 5-Chloro-
CAS No.	942316-71-4
Molecular Formula	C5H6ClNS
Molecular Weight	147.62 g/mol
Synonyms	5-Chloro-3-thiophenemethanamine; (5-Chlorothiophen-3-yl)methanamine; 5-Chloro-3-thienylmethylamine; 3-(Aminomethyl)-5-chlorothiophene; 5-Chloro-thiophene-3-methylamine; 5-Chloro-3-thiophenemethylamine; 5-Chloro-3-aminomethylthiophene
EINECS	Contact for details

Quality Control

Our production of 3-Thiophenemethanamine, 5-Chloro- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH guidelines, and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.