Description

Azepino[4,5-B]Indole-5-Carboxylic Acid, 1,2,3,6-Tetrahydro-1,1-Dimethyl-, 1-Methylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and oncological drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client drug programs.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Item	Detail
Product Name	Azepino[4,5-B]Indole-5-Carboxylic Acid, 1,2,3,6-Tetrahydro-1,1-Dimethyl-, 1-Methylethyl Ester
CAS No.	942145-77-9
Molecular Formula	C18H23NO2
Molecular Weight	285.38 g/mol
Synonyms	1,2,3,6-Tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylic acid 1-methylethyl ester; Isopropyl 1,2,3,6-tetrahydro-1,1-dimethylazepino[4,5-b]indole-5-carboxylate; 1,1-Dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid isopropyl ester; Azepinoindole ester derivative; CAS 942145-77-9
EINECS	Contact for details

Quality Control

Every batch of Azepino[4,5-B]Indole-5-Carboxylic Acid, 1,2,3,6-Tetrahydro-1,1-Dimethyl-, 1-Methylethyl Ester is manufactured and tested under a strict quality management system. We ensure compliance with ICH guidelines for impurities and utilize advanced analytical techniques (HPLC, GC-MS, NMR) to guarantee identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.