Description

5-Methyl-3-(trifluoromethyl)-1H-pyrazole is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of the pyrazole scaffold and the electron-withdrawing trifluoromethyl group, which is crucial for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances bioavailability and metabolic stability.
• Material Science: Serves as a precursor for functionalized ligands in catalysis and for the synthesis of advanced polymers with specific thermal or chemical resistance.
• Chemical Research: Employed in academic and industrial R&D for exploring new reactions in fluoroorganic chemistry and heterocyclic compound libraries.
• Ligand & Catalyst Development: Useful for constructing complex chelating agents and organocatalysts used in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	5-Methyl-3-(Trifluoromethyl)-1H-Pyrazole
CAS No.	942060-04-0
Molecular Formula	C5H5F3N2
Molecular Weight	150.10 g/mol
Synonyms	5-Methyl-3-(trifluoromethyl)-1H-pyrazole; 3-Trifluoromethyl-5-methyl-1H-pyrazole; 5-Methyl-3-trifluoromethylpyrazole; 1H-Pyrazole, 5-methyl-3-(trifluoromethyl)-; 942060-04-0; 5-Methyl-3-(trifluoromethyl)pyrazole
EINECS	Contact for details

Quality Control

Our 5-Methyl-3-(trifluoromethyl)-1H-pyrazole is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.