Description

2-Pyrrolidin-1-Yl-1,3-Thiazole-5-Carboxylic Acid is a high-value heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring fused pyrrolidine and thiazole rings, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential drug candidates targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug molecules, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific biological activity.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and asymmetric synthesis.
• Material Science Precursor: Potential intermediate for synthesizing organic semiconductors, conductive polymers, or advanced organic frameworks.
• Bioconjugation and Probe Synthesis: The carboxylic acid group allows for coupling to biomolecules, useful in creating diagnostic probes or biochemical tools.

Basic Information

Product Name	2-Pyrrolidin-1-Yl-1,3-Thiazole-5-Carboxylic Acid
CAS No.	941716-91-2
Molecular Formula	C8H10N2O2S
Molecular Weight	198.24 g/mol
Synonyms	1,3-Thiazole-5-carboxylic acid, 2-(1-pyrrolidinyl)-; 2-(Pyrrolidin-1-yl)-1,3-thiazole-5-carboxylic acid; 2-(1-Pyrrolidinyl)-1,3-thiazole-5-carboxylic acid; 5-Carboxy-2-pyrrolidin-1-yl-1,3-thiazole; Pyrrolidin-1-yl-thiazole-5-carboxylic acid; 941716-91-2; 2-Pyrrolidin-1-yl-1,3-thiazol-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-Pyrrolidin-1-Yl-1,3-Thiazole-5-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to in-house specifications aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as identity, purity, and impurity profile. We support cGMP compliance for advanced applications and can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.