Description

Methyl 3-(Aminosulfonyl)-5-Chlorothiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates a chlorothiophene core, a methyl ester, and a sulfonamide group, enabling its use in the development of novel active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of new chemical entities and intermediates. Its consistent quality and reliable supply are critical for accelerating discovery pipelines and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Agrochemical Research: Serves as a crucial precursor in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorothiophene moiety.
• Material Science: Used in the research and development of advanced organic electronic materials, such as semiconductors and conductive polymers, due to its electron-deficient thiophene structure.
• Chemical Synthesis: Acts as a versatile synthon for further functionalization, enabling the creation of complex sulfonamide and ester derivatives for various specialty chemical applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	Methyl 3-(Aminosulfonyl)-5-Chlorothiophene-2-Carboxylate
CAS No.	941239-79-8
Molecular Formula	C6H6ClNO4S2
Molecular Weight	255.70 g/mol
Synonyms	Methyl 5-Chloro-3-sulfamoylthiophene-2-carboxylate; 5-Chloro-3-sulfamoylthiophene-2-carboxylic acid methyl ester; 2-Carbomethoxy-5-chlorothiophene-3-sulfonamide; Methyl 5-chloro-3-sulfamoyl-2-thiophenecarboxylate; 941239-79-8; 5-Chlorothiophene-3-sulfonamide, 2-carbomethoxy-; Methyl (5-chloro-3-sulfamoylthiophen-2-yl)formate
EINECS	Contact for details

Quality Control

Our Methyl 3-(Aminosulfonyl)-5-Chlorothiophene-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support compliance with global regulatory frameworks, and our quality commitment is designed to meet the stringent requirements of pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.