Description

1-Benzenesulfonyl-4-Chloro-2-Iodo-7-Azaindole is a high-purity, multi-functionalized azaindole derivative designed for advanced pharmaceutical and agrochemical research and development. This compound serves as a critical synthetic intermediate, enabling the construction of complex molecular architectures through its reactive halogen and sulfonyl functional groups. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical industry for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile reactivity.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry: Used in route scouting and scale-up synthesis for active pharmaceutical ingredients (APIs).
• Custom Synthesis: Starting material for the preparation of more complex, tailored azaindole-based compounds for specialized research.

Basic Information

Product Name	1-Benzenesulfonyl-4-Chloro-2-Iodo-7-Azaindole
CAS No.	940948-30-1
Molecular Formula	C13H7ClIN2O2S
Molecular Weight	417.63 g/mol
Synonyms	4-Chloro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-1-(phenylsulfonyl)-; 4-Chloro-2-iodo-7-azaindole-1-benzenesulfonate; 7-Azaindole, 1-benzenesulfonyl-4-chloro-2-iodo-; 940948-30-1; 1-(Phenylsulfonyl)-4-chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-Benzenesulfonyl-4-Chloro-2-Iodo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.