Description

Benzenamine, 2-Iodo-5-(Trifluoromethoxy)- is a high-purity, advanced pharmaceutical intermediate (API) characterized by its unique halogenated aniline structure. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry where it serves as a key building block for drug discovery and development. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors seeking to incorporate a trifluoromethoxy-substituted aromatic amine into their target compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral drugs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and advanced organic electronic materials due to its electron-withdrawing substituents.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and as a versatile substrate for further functionalization in organic chemistry laboratories.
• Life Science Research: Utilized as a biochemical tool and probe in academic and industrial research for studying enzyme interactions and receptor binding.

Basic Information

Product Name	Benzenamine, 2-Iodo-5-(Trifluoromethoxy)-
CAS No.	940908-06-5
Molecular Formula	C7H5F3INO
Molecular Weight	302.02 g/mol
Synonyms	2-Iodo-5-(trifluoromethoxy)aniline; 2-Iodo-5-(trifluoromethoxy)benzenamine; 5-(Trifluoromethoxy)-2-iodoaniline; 1-Amino-2-iodo-5-(trifluoromethoxy)benzene; 2-Iodo-α,α,α-trifluoro-p-anisidine; 940908-06-5; 2-Iodo-5-trifluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our Benzenamine, 2-Iodo-5-(Trifluoromethoxy)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.