Description

3-Fluoro-6,7-Dihydro-5H-Benzocycloheptene is a high-value, fluorinated organic building block characterized by its unique seven-membered fused ring structure. This compound matters as a critical intermediate for advanced pharmaceutical research and the synthesis of complex agrochemicals, where the introduction of fluorine atoms is a key strategy for modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances lipophilicity and target binding.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers or liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to create complex, polycyclic compounds for discovery chemistry.
• Fluorine Chemistry Studies: Used as a model substrate in academic and industrial research to study the effects of fluorine on reaction mechanisms and molecular conformation.

Basic Information

Product Name	3-Fluoro-6,7-Dihydro-5H-Benzocycloheptene
CAS No.	939760-94-8
Molecular Formula	C11H11F
Molecular Weight	162.20 g/mol
Synonyms	3-Fluoro-6,7-dihydro-5H-benzo[7]annulene; 3-Fluorobenzocycloheptene; 3-Fluoro-5H-benzocycloheptene; 3-Fluoro-6,7-dihydro-5H-1-benzocycloheptene; 939760-94-8; 3-Fluoro-5H-1-benzocycloheptene; 3-Fluoro-6,7-dihydro-5H-benzo[a]cycloheptene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-6,7-Dihydro-5H-Benzocycloheptene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.