Description

4-Iodo-2,3-Dihydro-1H-Indole is a halogenated indoline derivative, a versatile and valuable synthetic intermediate in advanced organic chemistry. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the indoline core structure.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in bioconjugation chemistry for studying protein interactions.
• Catalyst & Ligand Synthesis: Used to create novel nitrogen-containing ligands for transition metal catalysis.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Iodo-2,3-Dihydro-1H-Indole
CAS No.	939759-03-2
Molecular Formula	C8H8IN
Molecular Weight	245.06 g/mol
Synonyms	4-Iodoindoline; 4-Iodo-2,3-dihydro-1H-indole; 1H-Indole, 4-iodo-2,3-dihydro-; 4-Iodoindolin; 2,3-Dihydro-4-iodo-1H-indole; 4-Iodo-2,3-dihydroindole; 4-Iodoindoline (6CI,7CI,8CI)
EINECS	Contact for details

Quality Control

Our 4-Iodo-2,3-Dihydro-1H-Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.