Description

1,2,3,4-Tetrahydro-5-Iodo-Isoquinoline is a halogenated isoquinoline derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its functionalized scaffold, which serves as a critical intermediate for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the isoquinoline pharmacophore.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the iodine atom allows for further functionalization to optimize biological properties.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1,2,3,4-Tetrahydro-5-Iodo-Isoquinoline
CAS No.	939758-80-2
Molecular Formula	C9H10IN
Molecular Weight	259.09 g/mol
Synonyms	5-Iodo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5-iodoisoquinoline; 5-Iodotetrahydroisoquinoline; THIQ-5-I; Isoquinoline, 1,2,3,4-tetrahydro-5-iodo-; 939758-80-2
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-5-Iodo-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.