Description

Methyl-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate CAS NO 939758-79-9 is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries who require a reliable, high-quality source for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with tetrahydroisoquinoline scaffolds.
• Neurological Research: Used in the development of compounds for studying and treating neurological disorders.
• Cardiovascular Drug Synthesis: Serves as a building block for APIs targeting cardiovascular diseases.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic structures in medicinal chemistry.
• Academic & Industrial R&D: A valuable reagent for research laboratories and process development teams exploring new chemical entities.
• Custom Synthesis: Used as a starting material for the custom manufacturing of specialty fine chemicals and APIs.

Basic Information

Product Name	Methyl-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate
CAS No.	939758-79-9
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydroisoquinoline-5-carboxylate; 5-Carbomethoxy-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-5-carboxylic acid methyl ester; Methyl 5,6,7,8-tetrahydroisoquinoline-6-carboxylate; 6-Methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline; MTIQC; THIQ-5-COOMe
EINECS	Contact for details

Quality Control

Our Methyl-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.