Description

[2-(2,4-Difluoro-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluorophenyl and carbamate functional groups. This compound is of critical importance for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and fungicides, where the difluorophenyl moiety can enhance biological activity and environmental stability.
• Chemical Synthesis: Used in organic synthesis for introducing protected amino alcohol functionalities into more complex molecular frameworks.
• Protease Inhibitor Development: Potential intermediate in the research and production of protease inhibitors, leveraging its carbamate group.
• Material Science: Exploration of its use in creating specialized monomers or ligands for advanced polymeric materials and catalysts.

Basic Information

Product Name	[2-(2,4-Difluoro-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No.	939757-31-0
Molecular Formula	C13H17F2NO3
Molecular Weight	273.28 g/mol
Synonyms	tert-Butyl N-[2-(2,4-difluorophenyl)-2-hydroxyethyl]carbamate; 2,4-Difluoro-β-hydroxy-phenethylamine N-BOC derivative; BOC-2,4-Difluoro-β-hydroxy-phenethylamine; N-BOC-2-Amino-1-(2,4-difluorophenyl)ethanol; 1-(2,4-Difluorophenyl)-2-[(tert-butoxycarbonyl)amino]ethanol; (2,4-Difluorophenyl)glycinol N-BOC; N-(tert-Butoxycarbonyl)-2,4-difluoro-β-hydroxy-phenethylamine
EINECS	Contact for details

Quality Control

Our [2-(2,4-Difluoro-Phenyl)-2-Hydroxy-Ethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity suitable for sensitive pharmaceutical synthesis. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.